L-glutamine is the most plentiful amino acid in the body, involved in protein synthesis and serving as fuel for the immune system. Most people benefit from taking l-glutamine when their immune system is weakened or for healing a major wound like a burn.
Typical L-Glutamine Dose for Leaky Gut Repair
Starting dose
- 4 grams once daily – Therapeutic dose (most commonly used)
- 4 grams 2–4 times per day
- Total: 8–16 grams per day
Higher therapeutic dose (short-term only if needed)
- Up to 20 grams per day, divided doses
Most people heal well within the 8–16 g/day range.
Best Time to Take L-Glutamine
Timing matters because it absorbs better without competing amino acids.
Take:
- First thing in the morning — empty stomach
- Between meals
- Before bed (optional extra dose)
- Avoid taking with protein meals.
Example schedule:
• Morning – 4 g
• Mid-afternoon – 4 g
• Before bed – 4 g
Mix powder in water (room temperature).
How Long to Take for Gut Repair
• Minimum: 4 weeks
• Ideal: 8-12 weeks
• Severe gut damage: 3-6 months
Each level scoop is 4 grams
The gut lining renews about every 3-5 days, but inflammation takes longer to calm.


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